Detalhe da pesquisa
1.
Combined in silico and in vitro approaches to identify P-glycoprotein-inhibiting pesticides.
J Biochem Mol Toxicol
; 38(1): e23588, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-37985955
2.
Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
Arch Toxicol
; 98(2): 425-469, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38147116
3.
An Evaluation of the Cytotoxic and Genotoxic Effects of the Marine Toxin C17-SAMT in Human TK6 and HepaRG Cell Lines.
Int J Mol Sci
; 24(9)2023 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37175512
4.
Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells.
Arch Toxicol
; 96(7): 2087-2095, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35419617
5.
Comparative in silico prediction of P-glycoprotein-mediated transport for 2010-2020 US FDA-approved drugs using six Web-tools.
Biopharm Drug Dispos
; 42(8): 393-398, 2021 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-34272891
6.
Synergic toxic effects of food contaminant mixtures in human cells.
Mutagenesis
; 2020 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32809012
7.
Differential interactions of carbamate pesticides with drug transporters.
Xenobiotica
; 50(11): 1380-1392, 2020 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-32421406
8.
Mixtures of Lipophilic Phycotoxins: Exposure Data and Toxicological Assessment.
Mar Drugs
; 16(2)2018 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-29385038
9.
Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes.
Chem Res Toxicol
; 30(2): 657-668, 2017 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27976871
10.
Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines.
Mar Drugs
; 12(8): 4616-34, 2014 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25196936
11.
New methodological developments for testing the in vitro genotoxicity of nanomaterials: Comparison of 2D and 3D HepaRG liver cell models and classical and high throughput comet assay formats.
Chemosphere
; 350: 140975, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38142884
12.
Hydrogen inhalation: in vivo rat genotoxicity tests.
Mutat Res Genet Toxicol Environ Mutagen
; 894: 503736, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38432775
13.
Fate and PPARγ and STATs-driven effects of the mitochondrial complex I inhibitor tebufenpyrad in liver cells revealed with multi-omics.
J Hazard Mater
; 442: 130083, 2023 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36206710
14.
In vitro genotoxicity potential investigation of 7 oxy-PAHs.
Environ Mol Mutagen
; 64(3): 176-186, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36757094
15.
In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT).
Environ Mol Mutagen
; 2023 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37942839
16.
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project.
Front Toxicol
; 5: 1220998, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37492623
17.
A co-culture system of human intestinal Caco-2 cells and lymphoblastoid TK6 cells for investigating the genotoxicity of oral compounds.
Mutagenesis
; 27(6): 631-6, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22844081
18.
Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection.
Environ Toxicol
; 27(5): 277-84, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-20725938
19.
In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop.
Mutat Res
; 723(2): 101-7, 2011 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-21473931
20.
Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Toxicol Appl Pharmacol
; 245(2): 256-63, 2010 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20307560